AI and biotech HopWD-DTA: a novel framework for drug-target affinity prediction fusing multi-hop neighborhoods and deep features. 2026-04-13 Accurate prediction of drug-target affinity (DTA) is crucial for accelerating drug discovery, but it remains a significant challenge. While deep learning methods have shown promise, many existing models struggle with representing long-range protein relationships within protein-protein interaction…
AI and biotech 3D printed drug delivery devices: recent promises and challenges. 2026-04-11 3D Printing (3DP) has gained decent pace in the past decade in the pharmaceutical and biomedical fields. The approval of 3D-printed medical devices has gained more attraction than that of 3D-printed drug products. However, concerns related to cost-effectiveness, efficacy, and large-scale manufacturi……
AI and biotech Bridging Guidance and Regulation: Interpreting the Draft Annex 22 on Artificial Intelligence in GMP Manufacturing. 2026-04-10 This paper builds upon Stassen et al. (2025), “Recommendations for Artificial Intelligence Application in Continued Process Verification,” to provide a detailed interpretation of the European Medicines Agency (EMA) Draft Annex 22-Artificial Intelligence (July 2025 draft) within…
Gene editing Cost-effectiveness of exagamglogene autotemcel gene-edited therapy in patients with transfusion-dependent β-thalassemia in the United States. 2026-04-09 Exagamglogene autotemcel (exa-cel) is a one-time nonviral gene-edited therapy approved in the United States (US) for treatment of patients aged ≥12 with transfusion-dependent β-thalassemia (TDT). Standard of care (SOC) for TDT includes regular red blood cell transfusions…
AI and biotech EcoRxAgent: an AI agent for generating economically substitutable prescriptions. 2026-04-08 The prescription is a critical bridge between medical diagnosis and therapeutic intervention, embodying a complex decision that balances medical evidence, clinical experience, and individual patient needs. However, the prescribing process faces significant challenges from rising drug costs and the e… PubMed ↗NPJ…
