2026년 4월 28일 Pubmed Today
Advanced Therapeutics Therapeutic targeting of BCL-2 during CART cell production augments potency through non-apoptotic adaptive changes. 2026-04-27 Targeting the BCL-2 family of proteins, key regulators of cellular apoptosis, with BH3-mimetics has been a major therapeutic goal to overcome cancer cell death resistance. However, beyond their canonical roles in apoptosis, BCL-2 proteins also play vital roles…
